|Canavan, M., Smyth, A., Bosch, J., Jensen, M., McGrath, E. R., Mulkerrin, E. C., et al. (2015). Does lowering blood pressure with antihypertensive therapy preserve independence in activities of daily living? A systematic review. American Journal of Hypertension, 28 (2), 273-279.
|Plain Language Summary:
Plain Language Title
Does lowering blood pressure preserve independence in activities of daily living? A systematic planned out, orderly, regular review
Review go over, check Question
How often do high-quality studies of therapy treatment action, medicine, therapy to lower blood pressure address activities of daily living? Do interventions to lower blood pressure make it easier to carry out activities of daily living?
Hypertension high blood pressure is a major risk chance factor cause, reason leading to functional impairment. Functional impairment is defined as difficulty, disability, or dependency for activities of daily living. Interventions to lower blood pressure may help individuals with hypertension high blood pressure to participate take part, join, share in daily life.
The literature search took place in December 2013.
The review go over, check includes clinical work, studies, a medical setting that involves patients trials of adults with hypertension high blood pressure or prehypertension. To be included, trials had to randomly assign participants to either antihypertensive therapy treatment action, medicine, therapy (to lower blood pressure) or a control manage, have power over, take care of therapy. treatment action, medicine, therapy The intervention care had to last for at least one year. Ninety-three studies met the inclusion criteria.
Only one study (1%) reported activities of daily living as a primary outcome. Nine studies (10%) reported activities of daily living as a secondary outcome. The review go over, check was able to include six studies in a formal meta-analysis. These studies showed that therapy treatment action, medicine, therapy to lower blood pressure was more effective works well, good, strong than other forms of therapy treatment action, medicine, therapy at maintaining the ability skill, are able, can to carry out activities of daily living.
Use of Statistics
When possible, the review go over, check combines results across studies in a formal meta-analysis. The results are reported as odds-ratios.
Quality of Evidence
The quality of included studies is high. A key limitation of the review go over, check is that only a few trials could be included in the meta-analysis. All studies were randomized controlled trials, the highest standard of evidence. A few studies had some risk chance of bias, but the six studies included in the meta-analysis had no evidence of publication bias or selective reporting.