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||Pecourneau, V., Degboe, Y., Barnetche, T., Cantagrel, A., Constantin, A., & Ruyssen-Witrand, A. (2018). Effectiveness of exercise programs in ankylosing spondylitis: A meta-analysis of randomized controlled trials. Archives of Physical Medicine and Rehabilitation, 99(2), 383-389, 389.e1.
||Exercise, functional limitations, intervention, literature reviews, musculoskeletal disorders, outcomes, physical therapy
||A systematic review and meta-analysis of randomized controlled trials (RCTs) was conducted to evaluate the effectiveness of exercise programs on disease activity and function in patients with ankylosing spondylitis (AS). Medline via PubMed and Cochrane Library were searched for reports of RCTs examining the effectiveness of exercise programs for AS published up to May 2017. After screening 190 abstracts, 26 reports were selected for detailed evaluation and finally, 8 trials with a total of 331 patients with AS were analyzed that assessed home-based exercise programs, swimming, Pilates training, or supervised exercises. The primary outcomes checked in each study were the changes in the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) and Bath Ankylosing Spondylitis Functional Index (BASFI) after the completion of exercise programs. Modalities of exercise were compared and the use of biologic therapy was reported. Four trials included patients receiving antitumor necrosis factor therapy. All trials except one showed a decrease in BASDAI and BASFI with exercise. The weighted mean difference was −0.90 for the BASDAI and −0.72 for the BASFI in favor of exercise programs. Despite the small number of patients and the heterogeneity of exercise programs in the RCTs included in this meta-analysis, its results support the potential of exercise programs to improve disease activity and body function in AS.
|Full-Text Availability Options:||https://www.ncbi.nlm.nih.gov/pubmed/28860095|