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Registry of Systematic Reviews - Search Results

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1. Citation: Babaei-Ghazani, A., Roomizadeh, P., Forogh, B., Moeini-Taba, S., Abedini, A., Kadkhodaie, M., . . . Eftekjarsadat, B. (2018). Ultrasound-guided versus landmark-guided local corticosteroid injection for carpal tunnel syndrome: A systematic review and meta-analysis of randomized controlled trials. Archives of Physical Medicine and Rehabilitation, 99(4), 766-775.
Keywords: Carpal tunnel syndrome, drugs, electrophysiology, literature reviews, medical technology, medical treatment, outcomes
Abstract: Study reviewed the literature comparing the effectiveness of ultrasound-guided versus landmark-guided local corticosteroid injections in patients with carpal tunnel syndrome (CTS). Cochrane Central Register of Controlled Trials, MEDLINE (PubMed), Embase (Ovid), and Web of Science databases were searched from inception to February 1, 2017, to identify relevant randomized controlled trials (RCTs). Two authors independently screened abstracts and full texts. The outcomes of interest were the Symptom Severity Scale (SSS) and Functional Status Scale (FSS) scores of the Boston Carpal Tunnel Questionnaire, and 4 electrodiagnostic parameters: compound muscle action potential (CMAP), sensory nerve action potential (SNAP), distal motor latency (DML), and distal sensory latency (DSL). Overall, 569 abstracts were retrieved and checked for eligibility; finally, 3 RCTs were included (181 injected hands). Pooled analysis showed that ultrasound-guided injection was more effective in SSS improvement (mean difference [MD] = −.46), whereas no significant difference was observed between the 2 methods in terms of the FSS (MD = −.25). There were also no statistically significant differences in improvements of CMAP, SNAP, DML, or DSL. This findings of this review suggested that ultrasound-guided injection was more effective than landmark-guided injection in symptom severity improvement in patients with CTS; however, no significant differences were observed in functional status or electrodiagnostic improvements between the 2 methods.
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Record Updated:2018-10-23

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