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Registry of Systematic Reviews - Search Results

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1. Citation: Paneroni, M., Simonelli, C., Vitacca, M., & Ambrosino, N. (2017). Aerobic exercise training in very severe chronic obstructive pulmonary disease: A systematic review and meta-analysis. American Journal of Physical Medicine and Rehabilitation, 96(8), 541-548.
Keywords:  COPD, exercise, intervention, literature reviews, physical medicine, pulmonary function, rehabilitation, respiratory disease
Abstract: Study evaluated the effectiveness of exercise training in patients with very severe chronic obstructive pulmonary disease (COPD). MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, and Cumulative Index to Nursing and Allied Health Literature databases were searched for relevant randomized controlled trials (RCTs). Studies involving subjects with very severe COPD enrolled in in-patient, outpatient, or home- or community-based training programs lasting at least 4 weeks compared to usual care (control group) were included. RCTs with outcome measures that assessed functional capacity by the 6-Minute Walking Test (6MWT) and/or health-related quality of life (HRQOL) assessed by the Chronic Respiratory Disease Questionnaire or St. George's Respiratory Questionnaire (SGRQ) were selected. Of 580 articles screened, 10 were included. All 10 studies included leg exercise training: cycling in three studies, treadmill walking in one, free walking in two, and a combination of these in four. Only one study12 included structured arm training (lifting dumbbells). The programs' duration ranged from 4 to 52 weeks with 1 to 5 sessions per week lasting 15 to 40 minutes each. The intervention group, performing aerobic exercise training, improved significant more than the control group on the improved in the 6MWT and SGRQ. This review suggests that exercise training improves exercise tolerance and HRQOL in patients with very severe COPD. However, because few studies on severely affected patients are available and the training programs are highly heterogeneous, larger RCTs are needed.
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Record Updated:2018-10-29

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